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Special attention is given to the “gold standards” of each category, like HLA-DRB1* polymorphisms, oligoclonal bands, vitamin D, and conventional and nonconventional imaging techniques.

Moreover, not adequately established but quite promising, recently characterized biomarkers, like TOB-1 polymorphisms, are further discussed.

This variety, though, leads inevitably to confusion in the effort of decision making concerning strategic and individualized therapeutics.

In this paper, our primary goal is to provide the reader with a list of the most important characteristics that a biomarker must possess in order to be considered as reliable.

Belize Though Belize has long made a splash with scuba divers, this small, English-speaking country also boasts prominence as a premier place for unearthing the mystery of the Mayas, and as a natural choice for eco-tourism.

Big Island (Kona)If you could look into the minds of people all over the world for their ideal vacation destination, what you would see is a picture of the Island of Hawaii.

Aruba Aruba is located deep in the Caribbean, just about 15 miles north of Venezuela.

It is only 20 miles long and 6 miles wide, making it the smallest of the Dutch Caribbean, or "ABC" Islands (Aruba, Bonaire, and Curaçao).

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With a perfect climate and stunning beauty at every turn, it is the archetype of paradise.

Bora Bora A tiny archipelago in French Polynesia known as the Society Islands which, in addition to Bora Bora, include Tahiti, Moorea, Huahine, and Raiatea/Manihi, contains all the ingredients for a perfect tropical paradise.

Stewart Park, across from the Code's Mill building.

This town was the site of the last fatal duel in Upper Canada. Kennedy, a friend of Alexander Graham Bell, installed a direct telephone connection between his home and office.

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